Newly-formed endothelial cells regulate myeloid cell activity ...

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Research Articles: Development/Plasticity/Repair

Newly-formed endothelial cells regulate myeloid cell activity following spinal cordinjury via expression of CD200 ligand

Merav Cohen1,§, Hila Ben-Yehuda1,§, Ziv Porat2, Catarina Raposo1, Siamon Gordon3 and Michal Schwartz1

1Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.2Department of Biological Services, Weizmann Institute of Science, Rehovot, Israel.3Sir William Dunn School of Pathology, The University of Oxford, Oxford, UK.

DOI: 10.1523/JNEUROSCI.2199-16.2016

Received: 11 July 2016

Revised: 18 November 2016

Accepted: 29 November 2016

Published: 19 December 2016

Author contributions: M.C., H.B.-Y., S.G., and M.S. designed research; M.C., H.B.-Y., and C.R. performedresearch; M.C., H.B.-Y., Z.P., and M.S. analyzed data; M.C., H.B.-Y., and M.S. wrote the paper; S.G. and M.S.contributed unpublished reagents/analytic tools.

Conflict of Interest: The authors declare no competing financial interest.

§These authors contributed equally to this work.

We thank S. Schwarzbaum for proofreading and M. Azoulay for handling the animals. This work was supportedby the EU Seventh Framework Program HEALTH-2011 given to M.S. (Grant no. 279017). M. Schwartz holds theMaurice and Ilse Katz Professorial Chair in Neuroimmunology.

Corresponding authors: Prof. Michal Schwartz; Weizmann Institute of Science, 76100 Rehovot, Israel,Tel: +972-89342467; Fax:+972-89346018; E-mail: michal.schwartz@weizmann.ac.il; Dr. Merav Cohen;Weizmann Institute of Science, 76100 Rehovot, Israel, Tel: +972-89346975; Fax: +972-89346018; E-mail:merav.cohen@weizmann.ac.il

Cite as: J. Neurosci 2016; 10.1523/JNEUROSCI.2199-16.2016

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