Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am...

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Transcript of Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am...

Malignant Bone Tumors

by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough

J Bone Joint Surg AmVolume 83(11):1728-1745

November 1, 2001

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 1-A and 1-B A ten-year-old boy with osteosarcoma in the knee.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 1-A and 1-B A ten-year-old boy with osteosarcoma in the knee.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Anteroposterior radiograph of the femur in a nineteen-year-old woman, revealing a Ewing sarcoma.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Photomicrograph of a typical Ewing sarcoma, showing small, round, uniform cells with scant cytoplasm (magnification, 60).

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 4-A and 4-B A seventeen-year-old girl with Ewing sarcoma in the right femur.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 4-A and 4-B A seventeen-year-old girl with Ewing sarcoma in the right femur.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Axial computed tomography scan revealing a large soft-tissue mass on the right side of the pelvis of a patient with Ewing sarcoma.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 6-A through 6-E A nineteen-year-old man with Ewing sarcoma in the proximal aspect of the femur.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 6-A through 6-E A nineteen-year-old man with Ewing sarcoma in the proximal aspect of the femur.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Axial magnetic resonance image made prior to chemotherapy, revealing a large circumferential soft-tissue mass and involvement of the intramedullary canal.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

The soft-tissue mass greatly decreased in size following neoadjuvant chemotherapy.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Postoperative anteroposterior radiograph of the proximal part of the femur after wide resection and reconstruction with use of an allograft-prosthesis composite.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Figs. 7-A through 7-E A forty-five-year-old woman who had pain in the left hip.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

A technetium-99 bone scan showing a marked increase in uptake in the proximal part of the left femur and no other apparent lesions.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Magnetic resonance imaging confirmed that the tumor involved the medullary cavity of the femur and extended into the soft tissue.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Computed axial tomography scan showing the amount of bone destruction and the soft-tissue extension.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.

Histological findings were consistent with an intermediate-grade chondrosarcoma.

C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745

©2001 by The Journal of Bone and Joint Surgery, Inc.