Let’s Play Gene Mutations Chromosomal Mutations.

Post on 18-Dec-2015

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Transcript of Let’s Play Gene Mutations Chromosomal Mutations.

Let’s Play

Gene Gene MutationsMutations

ChromosoChromosomal mal

MutationsMutations

Gene Gene Expression Expression

Part 1Part 1

Gene Gene Expression Expression

Part 2Part 2

DNADNA

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Gene Mutation

Chromosomal

Mutation

Gene Expression

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Gene Expression

2DNA RNA

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The type of gene mutation that only

affects a single amino acid.

What is a substitution mutation?

The type of gene mutation that causes

all of the following nucleotides to move to the left one space.

What is a deletion mutation?

DailyDouble!

Where is at the third base

(nucleotide) in the codon?

Gene mutation that causes all the

nucleotides that follow to move to the right one

space.

What is an insertion

mutation?

The term for the two types of mutations that affect all the remaining amino

acids in the polypeptide.

What is a Frameshift mutation?

When a chromosome has a portion of genetic information repeated, this type of mutation

has occurred.

What is a duplication mutation?

The type of mutation that involves the

removal of a part of the chromosome.

What is a deletion mutation?

This series of images illustrates this type of

chromosomal mutation.> >

What is DNA helicase?

What is an inversion mutation?

This is image is displaying this type

of mutation.

What is an inversion mutation?

What is a translocation

mutation?

DailyDouble!

There have been cases of Males with

chromosome XX. This is possible because of the

translocation of this region.

What is the SRY gene?

The complementary base pair for Adenine

in RNA.

What is Uracil?

The process of copying DNA onto

mRNA.

What is transcription?

The first step of gene expression

occurs here.

Where is the nucleus?

This enzyme creates mRNA by assembling free ribonucleotides

complementary to the DNA.

What is RNA Polymerase?

These noncoding regions must be

removed from the mRNA before it

leaves the nucleus.

What are introns?

This step of gene expression when the polypeptide is

assembled.

What is translation?

Locations in cytoplasm where translation takes

place.~two answers~

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What are the free floating

ribosomes and Rough ER?

This RNA brings the monomers of

proteins to the site of protein

synthesis.

What is the tRNA?

The organelle where translation

occurs.

What is the ribosome?

These codons signal to the

ribosome that the polypeptide has been finished.

What are UGA, UAA, and UAG?

The term we use to refer to the

structure of DNA.

What is a double helix or twisted

ladder?

This sugar, found in DNA, lacks an

oxygen when compared to the

sugar of RNA.

What is deoxyribose

sugar?

These are the four possible bases on

DNA.

What are adenine, thymine, cytosine,

and guanine?

Organelle that stores and

protects DNA.

What is the nucleus?

These are the building blocks of

nucleic acids.

What are nucleotides?

When compared to DNA the

structure of the RNA molecule is referred to as…

What is single stranded?

The sugar of ribonucleic acid.

What is ribose?

These four nitrogen bases

are found in ribonucleic acids.

What are adenine, uracil, cytosine, and guanine?

This is the role of-mRNA-rRNA-tRNA

DailyDouble!

What are to copy the info from DNA, a component of the

ribosome, and brings the amino acid to the

ribosome?

These are the three types of

RNA.~Full word, not just letter abbreviation~

What are messenger RNA, ribosomal RNA,

and transfer RNA?

Topic:

Mutations

The mutation The mutation between these two between these two DNADNA standsstands will will

have this result on have this result on the final polypeptide.the final polypeptide.Original: TAC-CAT-GTC-Original: TAC-CAT-GTC-

AGC-ATTAGC-ATTMutated: TAC-GAT-GTC-Mutated: TAC-GAT-GTC-

AGC-ATTAGC-ATT

Original DNA: TAC-CAT-GTC-Original DNA: TAC-CAT-GTC-AGC-ATTAGC-ATT

Mutated DNA: TAC-GAT-GTC-Mutated DNA: TAC-GAT-GTC-AGC-ATTAGC-ATT

Original: TAC-CAT-GTC-Original: TAC-CAT-GTC-AGC-ATTAGC-ATT

mRNA: AUG-GUA-CAG-mRNA: AUG-GUA-CAG-UCG-UAAUCG-UAA

AAs: Met-Val-Glu-Ser AAs: Met-Val-Glu-Ser

Mutated: TAC-GAT-GTC-Mutated: TAC-GAT-GTC-AGC-ATTAGC-ATT

mRNA: AUG-CUA-CAG-mRNA: AUG-CUA-CAG-UCG-UAAUCG-UAA

AAs: Met-Leu-Glu-SerAAs: Met-Leu-Glu-Ser

DailyDouble!