Support for Pharma and Life Sciences Innovation

John O’Dea, Enterprise IrelandBio Pharma SummitOctober 2012

2

Irish owned enterprise World Class Research

Inward Investment

3

3

21 Enterprise Ireland’s Role

Support for Start-ups

Support for Industry

Agenda

What I Will CoverWhat I Will Cover

Supporting Innovation in Pharma and Lifesciences

• Innovation-Led High Potential Start-ups

• Client company investment in R&D

• Commercial return from state research

• Collaboration between industry and academia

• Drawdown by industry and academia from FP7 etc

• Seed and Venture Funds

Commercialisation Fund

Commercialisation Fund - Stages/ Go-No GoCommercialisation Fund - Stages/ Go-No Go

C PlusC Plus

Support for commercialisation of research from third-level institutions

Typically 2- 5 YEARS

BenchBench MarketMarket

CF feasibilityCF feasibility

Third Level Spin Outs

12

28

56

67

95 93

118

58

137

3531 31

0

20

40

60

80

100

120

2005 2006 2007 2008 2009 2010 2011

Nu

mb

er

LOAs

Spin outs

Date for your diary; Wednesday 28th November

Aviva Stadium

Technology Centres(~€2 million p.a. over 5 years)

EU FP7, ESA

Industry Led Research projects(~€2-3 million over 2-3 years)

Innovation Partnerships(up to €300k over 18 months)

R&D Fund: Small Projects [<€150k]Large Projects [<€650k]

Innovation Vouchers ( €5K)

Budget

NumberPartners

CollaborationComplexity

Innovation Support for industry

Technology Centres• Irish companies, multinationals, research institutions

• Undertake market-focussed strategic R&D

• Industry led

• Enterprise Ireland and IDA Ireland

Usually based in a University with support from partner colleges to deliver

on the research needs of the companies

Biorefining & Bioenergy IT InnovationApplied NanotechnologyComposite MaterialsMicroelectronics

Food for HealthManufacturing ResearchEnergy EfficiencyInternational Energy CentreLearning Innovation

Technology Centres

Connected HealthFinancial ServicesCloud Computing

Data AnalyticsPharmaceutical Manufacturing

Pharmaceutical Manufacturing PMTC • Improve manufacturing competitiveness of Irish sites and

companies

• Undertake research in advanced manufacturing technology with application to Irish pharma industry.

• Source additional funding through company projects and EU programmes .

• Showcase advanced pharmaceutical manufacturing expertise

• Support academic-industry collaboration

Pharmaceutical Manufacturing PMTC Initial research focus

Process Analytical Technology (PAT) to improve cost competitiveness through

• Rapid Microbiological assays

• Continuous Processing – as opposed to batch

• Soft sensors for process monitoring and control

• API-Real Time Release

• Packaging/authenticate/trace and security.Brendan Lawlor, Interim Research Manager

Brendan.Lawlor@Enterprise-Ireland.com

Industry-led Research Networks (ILRP)

•  Medium-term 'shared agenda' research by groups of companies

• Research contracted to a publicly-funded research institution with funding from Enterprise Ireland

Animal Health

Finished Medical Devices & Medical Aids

Diagnostics

Innovation Partnerships

• Typically individual collaborative projects between companies and researchers

• Up to €300k

• Up to 80% funding from Enterprise Ireland

R&D Fund

Small company 45%Medium Company 35%Large Company 25%

Simplified Application for Small R&D Fund <€150k

So you want to start a technology business; How can we help? 

100 new HPSUs per year, 20% Life-science

Indigenous 37%

MNC 32%

3rd Level 10%

Serial Promoter 16%

Other 5%

Most HPSU Entrepreneurs were managers inIndigenous Companies or MultinationalsMost HPSU Entrepreneurs were managers inIndigenous Companies or Multinationals

Background of Promoters

Business PartnersBusiness Partners

Where’s Sally?

EI AssistanceThe support you can get from us depends on where you

are.

1. Get to Investor Readiness• Build Business Plan

2. Raising investment

3. Growing the Business

We’re a Development

Agency

Mentor

Feasibility Study

Trade Fairs

Market information

Innovation Voucher Value Proposition Workshop

Seed CapitalCertification

Business Angels

Technology Assessment

Introduction to VCs

Investor Ready WorkshopsPitch preparation

New Frontiers Programme

Get to Investor ReadinessA Range of Supports

Large Market Opportunity [especially if VC needed]Barriers to Entry [current, future?]

High Growth, ScalableHigh Gross Margins

Large Market Opportunity [especially if VC needed]Barriers to Entry [current, future?]

High Growth, ScalableHigh Gross Margins

What we look for at Seed Stage

HPSU Investment

EI funding depends on exports, jobs & cash need

EI Investment is in equity [CCRPs] Minimum of matching external fundingAverage initial investment €250k

Due Diligence - the Business Plan• Market Risks• Execution Risks• Financial Risks

Due Diligence - the Business Plan• Market Risks• Execution Risks• Financial Risks

Funding

VC Funds€520 million

Seed Funds€124 million

Pre-Seed

Applied Process Consulting

Applied Process Consulting