Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Baseline characteristics of new users of statins and non-users of statins aged 30-84 years in the QResearch derivation and THIN validation cohorts

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Adjusted HRs (95% CI) for moderate to severe myopathyModels also adjusted for age and body mass index

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Validation statistics for each model in the THIN and QResearch validation cohorts

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Adjusted HRs (95% CI) for acute renal failure Models also adjusted for age and body mass index

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Adjusted HR (95% CI) for moderate/serious

liver dysfunction

Models also adjusted for age and body mass index

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Adjusted HR (95% CI) for cataract

Models also adjusted forage and body mass index

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Predicted to observed risk of each outcome using the QResearch database

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47

Numbers needed to harm (NNH) or numbers needed to treat (NNT) and numbers of extra or prevented cases, for each outcome over 5 years in patients aged 35-74 free of

cardiovascular disease at baseline with QRISK2 score of 20%+

Hippisley-Cox J, Coupland C. Heart 2010;96:939-47