Dr. Mike Eisenmenger - Driving Pig Performance in a Changing World of Antibiotic Usage, Boehringer...

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Driving Pig Performance in a

Changing World of Antibiotic Usage

Mike EisenmengerLeman Conference 2015

Boehringer-Ingelheim Media Dinner

Seate,Jessica BIV-US-J
just added this in

Goals:• Excellent NGF performance: Nursery-Finish or W-F• Nursery mortality- >1%• Finish mortality- >2%• W-F Mortality- >3%

• ADG Nursery ->0.9 pound/day• Finish ADG->1.9 pounds/day• W-F ADG->1.65 pounds/day

Goals:• Excellent NGF performance: Nursery-Finish or W-F• Change of status of some metrics?

• Prevention vs. treatment• Limited antibiotic usage• No environmental issues• Clean, safe, bright environment• Site appearance

Goals:• Reduced need for antibiotics to control/treat infectious

disease• An “easy” pig to raise in nursery finish/W-F• Requires less daily health management input

• Less Antibiotic Injections• Number of pigs moved from the general population to hospital pens

due to injury or illness• Less daily health management labor

• Robust• Reduced illness, easily overcome health challenges• Less inflammatory response• Can better handle minor environmental issues

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How to Accomplish the Goals:• High Health Status (low number of diseases

transmitted from the farrowing house)• Eliminate the diseases that we can• Mycoplasma hyopneumonia• PRRS• APP

How to Accomplish the Goals:• Focused Biosecurity Programs• Keep out what we have worked hard to eliminate• Sow farms

• Filtration• Specialized load in/out rooms

How to Accomplish the Goals:• Focused Biosecurity Programs• Keep out what we have worked hard to eliminate

N/F & W-F• Building design/layout• Mortality removal• Shower in/out

How to Accomplish the Goals:• Robust Vaccination Program for the pathogens we can

not eliminate• Salmonella typhimurium/chloreasuis• E Coli- K88/F18• Ileitis• Circo virus• Erysipelas• PRRS• Streptococcus suis• Haemophilus parasuis (Hps)

Typical Vaccination Program• Sow Farm:• Ingelvac Circoflex/Mycoflex at wean- 2 cc/pig • Ingelvac PRRS MLV vaccine- at wean or in nursery depending

on sow farm vaccination program• Strep suis/Hps autogenous as needed

• Early nursery:• K88/F18 E. coli-oral• Enterisol Salmonella T/C- oral

• Late nursery:• Enterisol Ileitis- oral

Use Ileitis as an example• Most systems I see will have production losses if a

control program for ileitis is not utilized.• Most losses will be late finishing (most expensive time-

costs “all in”)

Production Systems• Sows in upper Midwest- 350,000• Farms make prrs negative weaned pigs consistently• Well down the road of myco elimination programs• Both straight line flow and commingled sow farm pig

flow• Nursery- finish and W-F flows

What drove systems to vaccination for ileitis?• Consistent late bloody diarrhea• Varies some by system but all see• In several- nearly every lot group if no control programs

• Late finish mortality• Can add 1-2% at end of turn

• High drug costs• Easy to add >$1.00/head in medications

• Logistics• Transportation

Use Ileitis as an example• Marketing nightmare• Drives antibiotic usage in and around the marketing

window!!• Pig size at time of treatment dictates a lot of antibiotic use

Use Ileitis as an example• Marketing nightmare• Consistent relapses of Ileitis once off antibiotics (pull

medications to meet withdrawal (WD) times and manage costs)• Drugs and WD

• Tylosin- 2 days water and 28 days injection• Lincomycin- 3 days water and 4 days injection• Tylvalosin- 3 days water

Use Ileitis as an example

Antibiotic usage in an ileitis outbreakGrams/1000 head finisher•Injections

• 250 grams linco/day

•Water• >3000 grams linco in water• >2500 grams tylan in water• >4000 grams tylvalosin in water

•Medication costs, production loss, mortality, increased labor, concern about antibiotic WD, unhappy caregivers, transportation changes…………….

Antibiotics used in prevention programs• Continuous feed med programs- • Tylosin feed->14,000 grams

• Per 1000 head barn

• Pulse feed programs• Tylosin feed->8000 grams

• Per 1000 head barn

Ileitis- Methods of Control• Continuous feed grade medications

• Expensive• High antibiotic use rate• End up here due to timing issues

• Pulse medication programs• Feed or water• Timing difficult to target in order to get correct control

• Variations group to group of exposure and concurrent issues

• Mass vaccination programs• Reliable• Predictable • Easy to do

Ileitis- Vaccination Program Outcome• If we see late clinical ileitis• Equals vaccine administration issues• Fully understood by Service Managers in field

• Reduction of antibiotic use• Decrease risk of antibiotic residue at marketing• Reduction in mortality• Full dose application- shorter antibiotic free window post

vaccine application• Better Protection• Better Return on Performance