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CoursePoliciesandSyllabusBI336-CellBiologyWinter2016

• Lecture:1:45-2:50MWF,CLSB1A001• Recitation:3:00-3:50F,CLSB1A001• Final:Monday,March14,12:30-2:20PM

• JeffreySinger,Ph.D.,AssociateProfessor,BiologyDepartment,PSU• Office:CLSB3N032• OfficeHours:M,W3:00PM-4:00PMandbyappointment(NOTE:forthisyoumustgo

tothisroom:CLSB5S021,theydonotletmeusemyofficeforstudentofficehours)• E-mail:jsinger@pdx.eduPleasedonotuseD2Ltocontactme!

• Tel:503-725-8742• BrittneyDavidge bdavidge@pdx.edu• BrianWendel bwendel@pdx.edu

1) Alberts et al.,MolecularBiologyof theCell, 6th Edition, 2014GarlandScience. HARDBACK • 978-0-8153-4432-2 - LOOSELEAF • 978-0-8153-4524-4.Thisisrequiredforboth334and336.Thisistherequiredtextandisthebookthereadingassignmentsarereferringto.

2) i>clicker,soldatbookstore,wewillusetheseforquizzesandinclassquestions.Note:THESEAREREQUIRED!Youneedtohavethemonthefirstday!Also,pleasemakesureyouregistertheseonline!Gototheiclickerwebsiteandselectregistration.Canuseiclicker,iclicker+oriclicker2.

1) PrinciplesofBiology(FULLYEAR)2) GeneralChemistry3) MolecularBiologyBI3344) OrganicChemistryrecommendedbutnotrequired.Biochemistryishelpfulbutnotrequired.

Theoverallgoalofthiscourseistogiveyouanideaofwhatcellsareandwhattheydo.Thisgoalwillbeaccomplishedby:

1) Examiningindividualcellularcomponents2) Consideringhowcellularcomponentsworktogetherinsidethecell

TimeandRoom:

Instructor/OfficeHours:

Textbook:

Prerequisites(note,thesearerequired,notsuggested):

SubjectMatterandGoals:

TAS:

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3) Lookingathowcellsadapttochangingenvironmentsbothas individualsandaspartsofcellularcommunities(tissues,organsetc,).

Myhopeisthatthiscoursewillgiveyouasolidfoundationoncellularformandfunctionforfuturebiologycourses.Ifyouleavethiscoursewithabasicideaofwhatcellsare,whatcellsdoandhowtheyaccomplishthevarietyoftaskstheyareresponsiblefor,thenIhavedonemyjob.

• Lecturepresentations• Supplementalreadingmaterials• Syllabusupdates• Topicsforrecitation

• Dailyquizzesduringclass,(1/5ofgrade),usingclickers.• TwoMidterms(1/5ofGradeeach)-Jan27thandFeb19thinclass.• Groupworkandquizduringrecitation-1/5ofgrade.• Onefinal(1/5ofGrade).March14th,Monday12:30PM-2:20PM.

• WewilltrytousecodeABfortheentirequarter!• Iwill ask a fewquestions sometimeduring the lecture about thematerial covered in the

previous lecture topic. Pleasedonot communicatewithothersduring thequiz. Youarewelcometolookatnotestoanswerthese;youwillhave90secondstoanswereachoneusingyour clicker. Thesewill comprise 20%of your grade, thus obtaining and registering yourclickerisveryimportant.

• Note,theseareworth50pointstotal.Therewillbemorethan50questions.Theextrasarethereforthosewhomustmissafew(sick,snow,etc.).Thus,therearenomakeups.

• Iwillalsoaskquestionsthatarenotgradedusingtheclickers.ThiswillserveasamethodtodeterminehowwellIamgettingthematerialacrosstotheclass.

• Pleasenote:Youareresponsibleformakingsurethebatteryisgoodinyourclicker,makingsureyouknowhowtousethem(instructionsareprintedonthem)andknowhowtochangetootherfrequenciesifaskedto.MakesurethatD2Lhasyourcorrectemailaddressaswell.

• Makeup exams are only given under extreme circumstances, e.g birth/death in family orillnessthatrequiresmedicalattention(notefrommedicalprofessionalrequired).

• Theinstructorwilldeterminetheformatanddateofthemakeupexamination.• Cheatingonanyexaminationorquizwillresultinazero.

Gradesforthisclasswillbebasedonyourperformanceon3exams,groupworkinrecitationanddailyquizzes.Therewillbe2hourlyexamsandafinalexam.Eachexamisworth50points,recitationisworth50pointsandthequizzeswillbeworthatotalof50points.Yourfinalgradewillbebasedonthetotalnumberofpointsearnedforthequarter:

A=90%ofthetopscoreintheclass

D2L:

Evaluation:

Notesonclickersandquizzes:

Makeup/Cheating:

Gradedetermination:

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B=80%ofthetopscore C=70%ofthetopscore D=60%ofthetopscore F=59%orlowerofthetopscore

RegradePolicy:Mustberequestedinwritingwithinaweekofreturnofexamination.Note:Entireexamwillberegradedandthegrademaygodown.

• Exams will likely involve multiple-choice, written short-answer, and drawing/labeling

diagrams.Formultiple-choiceexams,studentswillneedtoprovideascantronsheet.BesuretobringaformSC982-E*scantronsheettoeveryexam.*Thisisalargeform,notthesmalloneandhasnewfeatures;IhaveuploadedaPDFofthisformforyoutosee.

• ThereareNOmake-upexams (seebelow). It is yourobligation tobepresent to take thescheduledexams.Please,donottakethiscourseifyoucannotbepresentfortheexamsatthescheduledtimes.Thisisnotnegotiable.Theonlyacceptablereasonsformissinganexamareadeathinthefamily,seriousillnessverifiedbyadoctor’snote,orarequiredUniversitysanctionedevent.

• Ifyoutakethetestinthetestingcenteryoumustgetanappointmentforthecorrectday,takethetestwhentheclasstakesit,andinformmeatleastoneweekaheadoftimeforeachtest!!!!!

• Also,youareresponsibleforkeepingtrackoftimeduringtheexams!!

• Studentswhowishtomakeanauditoryorvisualrecordingofanyportionoftheclassmust

speakwiththeinstructoraheadoftime.• Anysuchrecordingisforpersonaluseonly.Itmaynotbeshared,copied,uploadedtothe

Internet,and/ordistributedwithoutwrittenpermission fromthe instructoraswellasanystudentwhoappearsorisheardintherecording.

• Accommodations are collaborative efforts between students, faculty and the Disability

ResourceCenter(DRC).• StudentswithaccommodationsapprovedthroughtheDRCareresponsibleforcontactingthe

facultymemberinchargeofthecoursepriortoorduringthefirstweekofthetermtodiscussaccommodations.

• StudentswhobelievetheyareeligibleforaccommodationsbutwhohavenotyetobtainedapprovalthroughtheDRCshouldcontacttheDRCimmediatelyat503-725-4150.

• Ifyouhavenotdonesoalready,pleasecompletetheSafeCampusModuleind2l.Themodule

shouldtakeapproximately30to40minutestocompleteandcontainsimportantinformationandresources.Ifyouorsomeoneyouknowhasbeenharassedorassaulted,youcanfindtheappropriateresourcesonPSU’sEnrollmentManagement&StudentAffairs:SexualPrevention& Response website at: http://www.pdx.edu/sexual-assault/. PSU's Student Code ofConductmakes itclearthatviolenceandharassmentbasedonsexandgenderarestrictlyprohibited and offenses are subject to the full realm of sanctions, up to and includingsuspensionandexpulsion.

Exampolicies:

Statementregardingrecordinganddistributionofcoursesessions:

Statementregardingstudentswithdisabilities:

SafeCampusModule:

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• Itakelearningveryseriouslyandviolationofthestudentconductcodewillnotbetolerated.

A copy of the student conduct code is provided by PSU at the following web address:http://www.pdx.edu/dos/psu-student-code-conduct.

• Thisclassandthetestswillbemoderatelydifficultsobepreparedfortheexamwhenyouarrive.Toensureafairtestingenvironmentnoonewillbeallowedtoleavethelecturehallduringtheexamuntiltheyturnintheirexamforfinalgrading.

• Remember:Theseareclosedbookexams!Also,allportableelectronicdevicese.g.phones,pagers,calculators,mp3players,GPSunits,etc…mustbestowedsafelyWITHINyourbookbagoryourpocketsduringtheexam.Headphonesarenotallowed.Noexceptions.

• Ifyouhaveamedicalproblemorlearningdisabilitythatmayinterferewithadheringtotheserulesandyouwishtoarrangeforspecialaccommodations,youmustseemeatleastoneweekbeforethefirstexam.ForpeopletakingtheexamatthetestingcentermakesureyoubooktimesearlyandIalwayspreferyoutaketheexamatthesametimeastherestoftheclass(starttime).

LectureswillbeavailableonlineusingD2L.Theseareanoutlineofwhatwascoveredinlectureandareprovidedtoassistyou.Thesefilesshouldnotbeconsideredacompletecoverageofthelecturematerialsandarecertainlynotanacceptablereplacementforattendinglectures.Inaddition,thesearenotnotes, theyaremerelyanoutlineofwhat Idiscussed inclass. Youshouldtakeyourownnotes.

Duringrecitationwewilldogroupworkinvolvingdiscussionandsolvingofproblemsincellbiology.Thiswillbelikeadrylabontopicsfromtheweek.Wewillalsohaveaquizeachweek.Thiswork(quizanddiscussion)willbeworth1/5ofyourtotalgrade,atotalof50points.

Iwillfollowtheuniversitypolicies.Thosepoliciesareshownhere:http://www.pdx.edu/registration/grading-system#/?section=incompletegradeiPleasereviewthese.

Examinationetiquette:

LecturePresentations:

Recitation:

Incompletes:

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SyllabusDate: LectureTopic: Reading: Recitationtopic:

Part1:CellularComponentsandMolecularTraffickingJan4 1.IntroductionandMembranesI-Structure Chapter10 Jan6 2.MembranesII-Proteins Chapter10 Jan8 3.MembranetransportI-Transporters Chapter11 Proteinsin

membranesJan11 4. Membrane transport II-Ion channels and the

electricalpropertiesofmembranes Chapter11

Jan13 5.Intercellularcompartmentsandtransportofmoleculesbetweennucleusandcytosol Chapter12

Jan15 6.Transportofproteinsintoorganelles Chapter12 TransportJan18 HOLIDAYJan20 7.TheERI-import Chapter12 Jan22 8.TheERII-folding,qualitycontrolandlipids Chapter12 FunctionofERJan25 9.TraffickingI-Compartments Chapter13 Jan27 Midterm1Jan29 10.TraffickingII-Golgi Chapters13 TraffickingFeb1 11.TraffickingIII-EndoandExocytosis Chapters13

Part2:CellularEnergeticsFeb3 12.EnergyconversionI-Electrontransport Chapter14 Feb5 13.EnergyconversionII-Photosynthesis Chapter14 Energy

ConversionFeb8 14.Plastidandmitochondrialgenetics Chapter14

Part3:HowCellularComponentsWorkTogetherFeb10 15.CellCommunication Chapter15 Feb12 16.SignalingMechanismsI-Gproteincoupledcell

surfacereceptors Chapter15 GPCRs

Feb15 17.SignalingMechanismsII-Enzymecoupledcellsurfacereceptors Chapter15

Feb17 18.SignalingMechanismsIII-Latentsignalingmoleculesandplantsignaling Chapter15

Feb19 Midterm2 SignalingMechanisms

Feb22 19.ThecytoskeletonI-FilamentsandActin Chapter16 Feb24 20.ThecytoskeletonII--MyosinsandMicrotubules Chapter16 Feb26 21.ThecytoskeletonIII-Intermediatefilaments

andcellpolarization Chapter16 Cytoskeleton

Feb29 22.ThecellcycleI-RegulationandPhasesI Chapter17 Mar2 23.ThecellcycleII-PhasesII Chapter17

Part4:HowCellsInteractAndRespondToTheirEnvironmentMar4 24.Apoptosis Chapter18 CellCycleMar7 25.CellinteractionsI-cell-cellinteractions Chapter19 Mar9 26.CellinteractionsII-cell-matrixinteractions Chapter19 Mar11 27.StemCells Chapter22 AdhesionMar14 FinalExam12:30-2:20PMMonday

Note:Theabovescheduleissubjecttochange,exceptforexamdates,whicharefixed.

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LastUpdated:December8,2015