A history of the most notorious zoonotic diseases · & re-emerging infectious diseases The economic...

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The animal health industry is actively working with governments and regulators around the world to try

to overcome the many challenges still existing to ensure that veterinary medicines can be delivered

quickly and effectively when needed

Salmonella costs the USA

as much as $3bn annually

World Zoonosis Day6TH July 2015

A history of the mostnotorious zoonotic diseases

i To find out more on how protecting our animals will help protect our world visit www.HealthforAnimals.org/who-we-are/zoonoses-outbreaks or join the debate on Twitter @HealthforAnimals

Global examples of emerging & re-emerging infectious diseases

The economic impact of recent zoonotic disease outbreaks

Up to 75% of all human diseases are zoonotic

in origin, meaning they are naturally

transmitted between animals and humans

Currently there are over 200 identified

zoonotic diseases that represent a clear threat

to our health and the welfare of animals

Up to 20% of global animal production is

lost to disease

The impact of zoonotic epidemics from 1995

to 2008, many of them preventable, exceeded

$120 billion globally

Some zoonotic diseases such as rabies

can be eradicated

Preventive veterinary medicines & the widespread

use & development of vaccines play an increasingly

important role globally in effective disease control

200+75% $$120Bn20%

A historical timeline of some of the most notorious zoonotic diseases demonstrates a highly probable increase in incidences over the years. This is most likely due to a growing population, increased globalisation, travel, international trade, pet ownership, socio-economic factors and climate change.

Black Death (plague) Europe 1347

Yellow fever South America16th century

Salmonella USA 1885

EbolaAfrica1976

Lyme diseaseUSA1975

H5N1 (avian influenza) China1997

Nipah virusMalaysia1999

Rabies Italy1546

Brucellosis Malta1850s

Cryptosporidiosis USA1907

Influenza pandemicGlobal1918

HIV / AIDSUSA1983

BSEEuropeMid 1980s

H1N1 Swine influenzaUSA 2009

SARS (Severe acute respiratory syndrome) China 2003

MERS-CoV Middle East Respiratory Syndrome coronavirus2012

E-coli Germany 1885

1200 AD

150

125

50

25

0

1990 1995 2000 2005 2010 2015

1300

1400

1500

1600

1700

1800

1900

2000

RISK

Newly emerging Re-emerging/resurging Deliberately emerging

Estim

ated

cost

($BN

)

Lassa fever

Hepatitis C

Lyme disease

Cyclosporiasis

vCJD

Cryptosporidiosis

HIV

Enterovirus 71

Hendra virus

Nipah virus

H5N1influenza

E. coli0157:H7

E. coli 0157:H7

Whitewater arroyo virus

Anthraxbioterrorism

Hantavirus pulmonary syndrome

SARS

Dengue Yellow fever Cholera Marburg hemorrhagic fever

Ebola hemorrhagic fever

Plague

Human monkeypox

Human monkeypox

West Nile virus

Rift Valley fever

Diptheria

Vancomycin-resistant

Staphylococcus aureus

Vancomycin-resistantStaphylococcus aureus

Drug-resistant malariaMultidrug-resistant tuberculosis

Typhoid fever

Credit: Bio Economic Research Associates, LLC ©., 12 August 2008. SARS and the New Economics of Biosecurity, 2003

EbolaAfrica

2014-15$1.6bnLyme disease

USA2002

$200m

H5N1 Avian influenza

Worldwide1997$30bn

Nipah virusAsia1999

$350-400m

BSE UK1995 $5bn

BSEUSA & Canada

2003-04$6.5bn

SARS China, Hong Kong, Singapore, Canada

2003 $30-50bn

E-coli 0157:H7USA2010

$489-993mn

H1N1 Swine influenza

Worldwide2009

$45-55bn

Rabies Worldwide

2013$124bn