Post on 14-Jan-2016
description
NIH Funding Mechanisms forPostdoctoral Fellows
Henry Khachaturian, Ph.D.NIH Extramural Program Policy OfficerActing NIH Research Training OfficerOffice of Extramural Research, NIH
Email: hk11b@nih.gov
5th Annual Institute on Postdoctoral PreparationSeptember 26, 2008
NIH Institutes and Centers (IC)
Intramural Research:
10%
R&D Contracts:11%
Research Project Grants:
53%
Other Research:6%
All Other:2%
Research Mgmt & Support:
5%
Research Training:
3%
Research Centers:
10%
FY 2008 Enacted Budget: $29.457 Billion
$761 Training $696 Career
$1,457 Million
$761 Training $696 Career
$1,457 Million
Ruth L. Kirschstein National Research
Service Award (NRSA) Program
Extramural Loan Repayment Program (LRP)
Research Career Development Award
(K) Program
Principal InvestigatorTeam Scientist
Postdoc orResidency
Grad orMed School
Undergraduate
Research Training and Career Timetable
Individual Predoc
Fellowship (F31)
Principal InvestigatorTeam Scientist
Postdoc orResidency
Grad orMed School
Undergraduate
Fellowships and Training Grants
Individual Postdoc
Fellowship (F32)
Institutional Training Grant
(T32)
0
1,000
2,000
3,000
4,000
5,000
6,000
7,000
8,000
9,000
10,000
11,000
12,000
13,000
14,000
Training Grants Fellowships
5,519 (41%)
Postdocs
1,600 (54%)
Postdocs1,370 (46%)
Predocs
8,097 (59%)
Predocs
Training Grants and Fellowships for FY 2006
Individual NRSA Postdoc Fellowship (F32)
Individual Fellow applies through
University/Institution
Training support based on research &
training plans and potential to become an
independent investigator
Up to 3 years of support; second year
repays service payback obligation.
Stipend: Not salary; subsistence allowance
to help defray living expenses
Fellow not an employees of either
Government or University
Current stipendlevels based onYears ofexperience:
0 = $36,9961 = $38,9762 = $41,7963 = $43,4284 = $45,0485 = $46,9926 = $48,8527 = $51,036
Tuition, Fees, and Health Insurance
Individual
FellowshipsPredoctoral Postdoctoral
Tuition/Fees Formula:
• 60% up to $16,000• 60% up to $21,000
for dual-degree
• 60% up to $4,500• 60% up to $16,000
for those seeking
additional degree
Institutional Allowance*• Public/Private Inst.• Fed./For Profit Inst.
$4,200
$3,100
$7,850
$6,750
* Help defray costs such as research supplies, equipment, Health Insurance,
fellow’s travel to scientific meetings and appropriate administrative costs.
F32 Fellowship Application
Use PHS 416-1: Paper Application
Transition to electronic application: Anticipated for August
2009
Application Submission Dates:
• April 8, August 8, December 8
Two-level review:
• Evaluation by Study Section (Peer Review)
• Evaluation by Institute Program Staff
• Generally 5-6 month period from receipt to earliest possible
award
• Check Program Announcements for variations
Fellowship Review Criteria
Candidate: Previous and current academic and research
performance; Potential, and commitment to biomedical research
career
Sponsor/Mentor and Training Environment: Quality of environment
and institutional commitment to training; Availability of
facilities/resources; and funding; Qualifications of mentor/sponsor for
proposed research training, and successful competition for research
support
Research Training Proposal: Merit of the proposal; Quality of
research training plan; Training as foundation for candidate’s
productive career
Training Potential: Value of the proposed fellowship experience as it
relates to the candidate's needs in preparation for a career as an
independent researcher
Helpful Hints for Fellowships
Read the Program Announcement and Contact NIH staff
Read the Instructions in the application kit
Observe Page limitations
Give yourself and your sponsor enough time
Give references enough time
Same training site?
Training should be appropriate considering previous experience
Capable and experienced sponsor? Co-sponsor?
Project should have merit as research and as training
mechanism
Arrange for pre-review
Mentored Scientist Career (K01)
Principal InvestigatorTeam Scientist
Postdoc orResidency
Grad orMed School
Undergraduate
Research Career Development Awards
Mentored Clinical Scientist Career
(K08)Pathway to
Independence (K99/R00)
Mentored Patient-Oriented Career
(K23)Quantitative Career Award
(K25)
Independent Scientist (K02)
Midcareer Patient-
Oriented (K24) Senior Scientist
Award (K05)
Career Awards for FY 2006
0
1,000
2,000
3,000
4,000
Early (Mentored) Mid-Career Senior
207 Institutional Awards
3,721Individual
Awards
234 Individual
Awards79
Individual Awards
Common Features: Eligibility
Who can Apply?
Read Program Announcements carefully
Research doctoral degree (K01, K02), but some require clinical
doctoral degree (K08, K23)
US Citizens, Non-Citizen Nationals, Permanent Residents
(except K99/R00)
Previous NIH Principal Investigators may be Ineligible
Usually Principal Investigator on R03 or R21 is OK (except
K99/R00)
Principal Investigator on R01 or subproject Principal Investigators
on a P01 is not OK
Three, Four, or Five years
depending on mechanism and justification of need
Extensions in time – award terms remain in effect (i.e. minimum
effort, no salary from other federal funding source)
Entry level awards require a mentor, multiple mentors are
encouraged
Mentored K awardees are encouraged to apply for independent
support during the K award
Common Features: Duration
Common Features: Effort
At least 75% effort committed to research
and the rest on other career development activities
Policy: Awardee must have a full-time appointment (12 person
months) at applicant institution, and the minimum effort
requirement must be covered by that appointment
Policy Update: Mentored K awardees in final 2 years may
reduce effort (to minimum of 50%) on K if replaced by effort as
Principal Investigator on research project or subproject of Center
grant, provided they remain in mentored situation
Temporary reduction permissible in unusual and pressing
circumstances
Vary widely across NIH Institutes and Centers
Read specific announcements carefully
Salaries capped between $75,000 and legislated cap ($191,300 for FY
2008)
Fringe benefits are in addition to any cap, plus 8% F&A costs
Salary supplementation OK, but must be from non-Federal sources and
must not require extra duties that would interfere with K activities
Research costs: Generally $25,000 to $50,000 and commonly used for
supplies, equipment, technical personnel, travel to research meetings or
training, tuition/fees, computational services
Ancillary personnel support is not allowed, such as salary for
administrative/secretarial support, support for mentors
Common Features: Costs
Common Features: Application
Use PHS Form 398: Career Award Section
Transition to electronic application: Anticipated for February
2009
Application Submission Dates:
• February 12, June 12, October 12
See also special instruction in a particular Funding Opportunity
Announcement
Institutes and Centers use of career awards is highly variable!
So… read the announcement carefully and call the NIH staff!
In K announcements, see contact web-table in for participating
Institutes and Centers
K01: Option for Research Doctorates
Provides an intensive, mentored research experience for a
period of up to 5 years Minimum of 75% full-time professional effort is required (based
on 12 person months appointment) Candidates must have a research doctorate and postdoctoral
experience Caution: Not an extension of postdoctoral training! Varied and limited NIH Institute and Center (IC) participation
• Some ICs use for re-entry• Some ICs use to pursue new research area
Requires plan for independence
K08: Option for Health Prof. Doctorates
Supervised research experience for individuals who are
committed to a career in laboratory or field-based research
Minimum of 75% full-time professional effort is required (based
on 12 person months appointment)
Candidates must have a health professional doctorate, but may
or may not have postdoctoral experience
Potential for phased award periods:
• didactic experience
• “hands-on” research experience
Usually supports non-patient-oriented research
K23: Option for Patient-oriented Research
Supervised study and research career development for
clinically trained professionals with a commitment to patient-
oriented research
Minimum of 75% full-time professional effort is required (based on
12 person months appointment)
Candidates must have a health professional doctorate, but may or
may not have postdoctoral experience
Must have completed clinical training, (including specialty and
sub-specialty if applicable) prior to award
May submit application prior to completion of clinical training
Patient-Oriented defined as research conducted with human
subjects, or material of human origin such as tissues, specimens
K25: Option for Quantitative Scientists
Mentored experiences for scientists from quantitative and
engineering backgrounds interested in pursuing health-
related research
Minimum of 75% full-time professional effort is required (based
on 12 person months appointment)
Candidates must have a research doctorate and ideally some
postdoctoral experience
Unique among NIH K awards in that eligibility spans the
postdoctoral to senior faculty levels, although some Institutes
have exceptions to this general rule
K99/R00: Option for Career Transition
Provides up to 5 years of support in two distinct phases:
Mentored and Non-Mentored
K99 phase: Mentored research experience for up to 2 years
R00 phase: Independent scientist phase for transition to
independence as junior faculty (up to 3 years)
Applicants may have no more than 5 years of postdoctoral training
at the time of initial application or any resubmissions
K99 is unique among NIH K awards in that both U.S. citizens and
non-U.S. citizens may apply
Domestic institutions only (both phases)
Transition to R00 phase requires offer and acceptance of tenure-
track, full-time assistant professor position, or equivalent
Common “K” Review Criteria (1 of 3)
Candidate: Potential to develop as an independent and productive
researcher; Quality of the letters of reference; Mentor(s) Statement
Career Development Plan: Likelihood that plan will contribute
substantially to the scientific development of candidate leading to scientific
independence
Research Plan: Scientific and technical merit of the research question;
Relevance to candidate's career objectives
Statements by Mentor(s), Consultant(s), and Collaborator(s): Mentor's
qualifications in proposed research; Role in providing guidance to the
candidate; Previous experience and history of research productivity
Environment and Institutional Commitment to the Candidate:
Commitment of institution to ensure that a minimum of 75% of the
candidate's effort will be devoted directly to research
Helpful Hints for “K” Applicants
Read the Program Announcement carefully and contact NIH
Program staff
Call NIH Program Staff
Read the Instructions in the application kit
Give yourself and your mentor(s) enough time
Give your references enough time
Training or career development plan should be appropriate
considering previous experience
Capable and experienced mentor/sponsor? Co-sponsor?
Project should have merit as research and as training or career
development vehicle
Arrange for pre-review
Transition to Electronic Applications
February 12, 2009: Research Career Development
(all Ks except K12)
August 8, 2009: Individual National Research
Service Awards (F)
September 25, 2009: Institutional National Research
Service Awards and Other Training Grants (T, D),
D43, D71/U2R and K12