No Disclosure

Mor-Avi et al JACC 2008 and Circulation 2009

Arruda et al Am J Cardiol 2001;87:1069-73. Chuah et al Circulation 1998;97:1474-80

Rest Low-dose dobutamine

Wall motion and thickening

Rest Low-dose dobutamine

LV ejection fraction

Rest

LV EF = 36%

Low-dose dobutamine

LV EF = 45%

Jacobs Eur Heart J 2006; 27: 460-468

Jenkins JACC 2004

2D 3D

Jenkins AJC 2007

Eroglu et al Eur Heart J 2006: 27, 1719–1724

Accurately localize and estimate the severity of stress-induced

ischemia by identifying areas of delayed contraction

Global longitudinal strain assessment

LDD GLS = - 12%

Rest GLS = - 10%

Global radial strain assessment

LDD GRS = 30%

Rest GRS = 24%

Aggeli et al Heart 2007;93:672-75

2D 3D

Badano et al J Am Soc Echocardiogr 2010;23:628-35

Lang et al , EJCI 2012

Breath holding during stress

Lang et al , EJCI 2012

Courtesy of I. Felekos

SVD MVD

Aggeli et al European Journal of Echocardiography (2011) 12, 648–655

Seo et al Circ Cardiovasc Imaging. 2009;2:451-459.

X = dobutamine infusion

Pratali et al Cardiovascular Ultrasound 2010, 8:10

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−

−

−

−

−

−

Sicari et al. European Journal of Echocardiography 2008

Pratali et al Cardiovascular Ultrasound 2010, 8:10 Badano et al J Am Soc Echocardiogr 2010;23:628-35

2D ECHO 3D ECHO P

Acquisition time 65 +/- 30 16 +/- 3 P<0.0001

Analysis time 176 +/- 63 91 +/- 5 P<0.0001

Varnero Cardiovascular ultrasound 2008 Badano et al J Am Soc Echocardiogr 2010;23:628-35

Thavendiranathan P JACC Cardiovasc Imaging. 2012 Mar;5(3):239-51

Badano L P et al. Eur Heart J Cardiovasc Imaging 2012;

Real-time segmentation → Real-time volume measurements!

Barbosa et al Int J Cardiovasc Imaging. 2012 Aug 1. [Epub ahead of print]

Sicari et al. Cardiovascular Ultrasound 2006, 4:11

K. Saito et al. Journal Am. Soc.Echocardiography 2009 J. Crosby et al., Ultrasound in Medicine & Biology 2008